osteomyelitis ( RID3715 ) vs solitary or initial form of Chronic Recurrent Multifocal Osteomyelitis (CRMO)
Distal tibial destructive change with edema. CRMO may be solitary and is often a diagnosis of exclusion where a patient is diagnosed with osteomyelitis and treated with antibiotics and is non responsive to the antibiotics. CRMO is widely believed to be a pediatric equivalent of SAPHO syndrome.4 SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis and osteitis) is an inflammatory bone disorder that commonly presents with skin manifestations. Although most patients present with a single symptomatic site, other sites of disease become apparent at imaging or during clinical follow-up [ Article ]

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