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Botox Myonecrosis Calf leg rim enhancing abscesses relating to botox injection. Botox, botulinum toxin type A, Clostridium perfringens toxin. Myoneural blocking agent for treating tremors, muscular spasticity following a cerebral vascular accident, cerebral paralysis. Myotoxicity due to phospholipase action – degenerative necrosis of skeletal muscle irrespective of the action of the neuron.